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An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
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Adapting HIV prevention evidence-based interventions in practice settings: an interview study.

Rosemary C Veniegas1, Uyen H Kao, Ricki Rosales

  • 1UCLA Department of Family Medicine and Center for HIV Identification, Prevention and Treatment Services, Los Angeles, CA, USA. rveniegas@mednet.ucla.edu

Implementation Science : IS
|November 26, 2009
PubMed
Summary

Community staff adapt human immunodeficiency virus (HIV) prevention interventions through modification and reinvention. Technical assistance is crucial during pre-implementation for effective technology transfer and to ensure interventions align with original goals.

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Area of Science:

  • Public Health
  • Health Services Research
  • Intervention Science

Background:

  • Evidence-based interventions (EBIs) are adapted to enhance external validity in real-world settings.
  • Adaptations occur across pre-implementation, implementation, maintenance, and evolution phases.
  • Two key adaptation categories: modification of intervention characteristics and reinvention (adding/deleting core elements).

Purpose of the Study:

  • Examine intervention adaptations during human immunodeficiency virus (HIV) prevention technology transfer.
  • Investigate modifications and reinventions of EBIs.
  • Understand adaptation processes in community-based settings.

Main Methods:

  • Qualitative study involving 34 community-based organization staff in Los Angeles.
  • Two interviews per participant, professionally transcribed.
  • Interviews coded by two coders with high inter-rater reliability (kappa = 0.73).

Main Results:

  • Participants described modifications and reinventions across all phases.
  • No participants reported accessing technical assistance when reinventing interventions.
  • Staff implemented recommended adaptation steps for new populations and settings.

Conclusions:

  • Staff frequently modify and reinvent interventions during HIV prevention program translation.
  • Targeted technical assistance for formative evaluation is needed, especially in the pre-implementation phase.
  • Continuous fidelity measurement and guidance are essential for effective reinvention and technology transfer.