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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Transcatheter aortic valve implantation
Samir R Kapadia1, E Murat Tuzcu
1Department of Medicine, Cleveland Clinic, 9500 Euclid Avenue, J2-3, Cleveland, OH 44195, USA.
Current Treatment Options in Cardiovascular Medicine
|November 26, 2009
Summary
Transcatheter aortic valve implantation (TAVI) offers a promising alternative for elderly patients with severe aortic stenosis who are high-risk surgical candidates. Current data show TAVI has an acceptable safety profile and effectively relieves aortic stenosis symptoms.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Geriatric Cardiology
Background:
- Aortic stenosis is a prevalent valvular heart disease in the elderly.
- Surgical aortic valve replacement is standard but high-risk for many patients.
- Medically treated severe aortic stenosis leads to poor outcomes.
Purpose of the Study:
- To evaluate transcatheter aortic valve implantation (TAVI) as a treatment option for severe aortic stenosis.
- To review current TAVI devices and their safety and efficacy.
- To discuss the potential expansion of TAVI to lower-risk patient groups.
Main Methods:
- Review of existing clinical data and investigational devices for TAVI.
- Focus on the Edwards Sapien and CoreValve systems.
- Analysis of TAVI complications and future technological advancements.
Main Results:
- TAVI devices demonstrate an acceptable safety profile.
- TAVI provides excellent hemodynamic relief for aortic stenosis.
- Current TAVI use is primarily in high-risk or inoperable patients.
Conclusions:
- TAVI is a viable treatment for high-risk elderly patients with severe aortic stenosis.
- Ongoing technical advancements may broaden TAVI applicability to moderate and low-risk patients.
- Future studies are needed to confirm TAVI's role in broader surgical risk populations.
