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Published on: February 11, 2022
Postoperative atrial fibrillation is associated with late mortality after coronary surgery, but not after valvular
Giovanni Mariscalco1, Karl Gunnar Engström
1Department of Surgical Sciences, Cardiac Surgery Unit, Varese University Hospital, Varese, Italy. giovannimariscalco@yahoo.it
Insights
Postoperative atrial fibrillation (AF) increases late mortality after isolated coronary artery bypass graft (CABG) surgery. AF did not significantly impact survival after valvular procedures, highlighting the need for strict postoperative surveillance.
Area of Science:
- Cardiology
- Cardiac Surgery
- Clinical Outcomes
Background:
- Atrial fibrillation (AF) is a common complication after cardiac surgery.
- Limited data exist on the association between postoperative AF and long-term mortality.
- The impact of AF on survival after different types of cardiac surgery requires further investigation.
Purpose of the Study:
- To investigate the association between postoperative atrial fibrillation (AF) and late mortality after cardiac surgery.
- To determine if AF following coronary artery bypass graft (CABG) surgery affects long-term survival.
- To assess the impact of AF on survival after valvular surgery and combined procedures.
Main Methods:
- A retrospective study of 9,495 cardiac surgery patients (1994-2004).
- Patients undergoing coronary artery bypass graft (CABG), valvular surgery, or combined procedures were analyzed.
- Long-term survival data were obtained from the Swedish population registry and analyzed using Cox proportional hazards models.
Main Results:
- Overall AF incidence was 26.7%, with higher rates in valvular and combined procedures.
- Postoperative AF was independently associated with increased long-term mortality in CABG patients (HR 1.22).
- AF was not significantly associated with long-term survival after isolated or combined valvular surgery.
Conclusions:
- Postoperative AF increases late mortality exclusively after isolated CABG surgery.
- The association between AF and late mortality was not statistically confirmed for valvular procedures.
- Findings suggest potential AF recurrence post-discharge, necessitating vigilant postoperative monitoring.
Background:
Numerous studies have attempted to determine the etiology and prophylactic measures concerning atrial fibrillation (AF) after cardiac surgery. However, limited data are available analyzing the association between postoperative AF and late mortality. We sought to determine if AF after cardiac surgery affects postoperative survival.
Methods:
All cardiac surgery patients (n = 9,495) undergoing cardiac surgery between January 1994 and December 2004 were studied. The study population comprised coronary artery bypass graft surgery (CABG [n = 7,621]), valvular surgeries (n = 995), and their combination (n = 879). Patients affected by postoperative AF were identified, and long-term survival was obtained from Swedish population registry and evaluated using Cox proportional hazards methods to adjust for baseline differences.
Results:
The overall AF incidence was 26.7%, subdivided into 22.9%, 39.8%, and 45.2% for CABG, valve surgery, and combined procedures, respectively. The median follow-up for the entire study population was 7.9 years (maximum, 13.4). Postoperative AF independently affected long-term survival in CABG patients (hazard ratio 1.22; 95% confidence interval: 1.08 to 1.37). For isolated valvular surgery or combined procedures, AF was not significantly associated with long-term survival (hazard ratio 1.21, 95% confidence interval: 0.92 to 1.58; and hazard ratio 1.15, 95% confidence interval: 0.90 to 1.46, respectively).
Conclusions:
Postoperative AF increases late mortality after isolated CABG surgery only. This finding was not statistically confirmed after isolated or combined valvular procedures. Our results draw the attention to possible AF recurrence after hospital discharge, indicating a strict postoperative surveillance.
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