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Electroporation-Based Genetic Modification of Primary Human Pigment Epithelial Cells Using the Sleeping Beauty Transposon System
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Pigmentary disorders.

Paul T Rose1

  • 1Academic Alliance in Dermatology, 4238 West Kennedy Boulevard, Tampa, FL 33609, USA. paultrose@yahoo.com

The Medical Clinics of North America
|November 26, 2009
PubMed
Summary
This summary is machine-generated.

This review covers common pigmentary disorders encountered by general practitioners, emphasizing the need to identify signs of serious underlying conditions for early diagnosis and treatment. It also highlights the emotional impact of cosmetic pigmentary issues, requiring patient support.

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Quantification of Hypopigmentation Activity In Vitro
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Area of Science:

  • Dermatology
  • Internal Medicine

Background:

  • Pigmentary disorders are common dermatologic conditions.
  • General practitioners (GPs) frequently encounter these disorders.
  • Recognizing pigmentary changes is crucial for diagnosing underlying diseases.

Purpose of the Study:

  • To review common pigmentary disorders relevant to internists and GPs.
  • To emphasize the importance of recognizing pigmentary changes indicative of serious illness.
  • To guide clinicians on patient management, including evaluation, treatment, and referral.

Main Methods:

  • Review of common pigmentary disorders.
  • Clinical recognition of pigmentary changes.
  • Diagnostic evaluation strategies.
  • Management approaches for cosmetic and medically significant conditions.

Main Results:

  • Certain pigmentary changes can signal serious underlying diseases like malignancy.
  • Early detection and evaluation are vital for timely treatment and specialist referral.
  • Cosmetic pigmentary disorders, while not life-threatening, can cause significant emotional distress.

Conclusions:

  • Clinicians must be adept at identifying pigmentary disorders.
  • Distinguishing between serious and cosmetic pigmentary issues is essential for appropriate patient care.
  • Management should encompass medical treatment, emotional support, and specialist referral when necessary.