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Related Experiment Video

Updated: Jun 18, 2026

Generation of Airway Epithelial Cell Air-Liquid Interface Cultures from Human Pluripotent Stem Cells

Generation of Airway Epithelial Cell Air-Liquid Interface Cultures from Human Pluripotent Stem Cells

Published on: June 14, 2022

Bronchiolar progenitor cells.

Huaiyong Chen¹, Keitaro Matsumoto, Barry R Stripp

¹Division of Pulmonary, Allergy and Critical Care Medicine, Duke University Medical Center, 106 Research Drive, Durham, NC 27710, USA.

Proceedings of the American Thoracic Society

|November 26, 2009

Summary

This summary is machine-generated.

Understanding airway epithelial repair is key to chronic lung disease. New models and technologies offer insights into lung progenitor cells for improved tissue repair strategies.

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Last Updated: Jun 18, 2026

Generation of Airway Epithelial Cell Air-Liquid Interface Cultures from Human Pluripotent Stem Cells

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Published on: June 14, 2022

Isolation of Basal Cells and Submucosal Gland Duct Cells from Mouse Trachea

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Isolation and Enrichment of Human Lung Epithelial Progenitor Cells for Organoid Culture

Isolation and Enrichment of Human Lung Epithelial Progenitor Cells for Organoid Culture

Published on: July 21, 2020

Area of Science:

Pulmonary Medicine
Cell Biology
Regenerative Medicine

Background:

Epithelial maintenance and repair are crucial for lung health.
Dysfunction in these processes contributes to chronic lung diseases.
Pulmonary airway remodeling is a hallmark of lung disease progression.

Purpose of the Study:

To review current concepts in airway epithelial repair.
To highlight advances in understanding lung progenitor cell biology.
To explore new strategies for modulating epithelial cell behavior in lung disease.

Main Methods:

Review of recent research in airway epithelial repair.
Analysis of new models for studying lung epithelial progenitor cells.
Discussion of emerging technologies for lung epithelial cell fractionation and culture.

Main Results:

New models provide insights into lung epithelial progenitor cell regulation and function.
Advanced cell culture techniques allow for controlled investigation of progenitor cell subsets.
Recent work clarifies the roles of progenitor cells in normal lung maintenance and repair.

Conclusions:

Advances in understanding lung epithelial progenitor cells are significant.
New technologies offer promising avenues for therapeutic interventions.
Modulating epithelial cell behavior may lead to novel treatments for lung diseases.