Related Experiment Video
Updated: Jun 18, 2026

Characterization of Membrane Transporters by Heterologous Expression in E. coli and Production of Membrane Vesicles
Published on: December 31, 2019
Ureide catabolism in Arabidopsis thaliana and Escherichia coli
Andrea K Werner1, Tina Romeis, Claus-Peter Witte
1Freie Universität Berlin, Institut für Biologie, Abteilung Biochemie der Pflanzen, Berlin, Germany.
Abstract:
The availability of whole genome sequences boosts the identification of biochemical pathways conserved across species using tools of comparative genomics. A cross-organism protein association analysis allowed us to identify two enzymes, ureidoglycine aminohydrolase and ureidoglycolate amidohydrolase, that catalyze the final reactions of purine degradation in the model plant Arabidopsis thaliana. A similar pathway was found in Escherichia coli, while an alternative metabolic route via ureidoglycine transaminase can be predicted for other organisms.
Related Concept Videos
Amino Acid Catabolism
Stringent Response in E. coli
Urea Cycle
Overview of Archaea
Biosynthesis in Bacteria

