Related Experiment Video
Updated: Jun 18, 2026

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
Published on: November 30, 2016
Muscle atrophy in cancer: a role for nutrition and exercise
Marina Mourtzakis1, Megan Bedbrook
1Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada. mmourtza@healthy.uwaterloo.ca
Abstract:
Developing successful antineoplastic therapies has been a primary focus of cancer research, whereas less attention has been directed at body composition and metabolism in cancer patients. Here, we examine the metabolic implications of muscle atrophy in cancer as well as the potential factors that contribute to muscle atrophy, including energy imbalance, hormone perturbations, and inflammation. The role of nutrition and exercise interventions in maintaining muscle mass during the cancer trajectory is examined.
Related Concept Videos
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Cross-bridge Cycle
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Muscle Recovery and Fatigue
Cancer Prevention
Some...
