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Updated: Jun 18, 2026

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
Published on: May 6, 2020
[Sports and osteoarthrosis]
1Klinik für Orthopädie und Unfallchirurgie, Medical Park Berlin Humboldtmühle, An der Mühle 2-9, 13507, Berlin, Deutschland. m.schaefer@medicalpark.de
Abstract:
Many risk factors for developing osteoarthrosis exist. Osteoarthrosis is the most common cause of chronic disability in middle-aged and older people. On the one hand, physical exercise can lead to arthrosis; on the other hand, physical exercise is commonly used in preventing and treating it. Experimental and clinical studies have shown that increased high-impact running or competitive sports result in a higher risk for osteoarthrosis than moderate low-impact running. In particular, sudden-impact loading and twisting movements of the joints can result in premature osteoarthrosis. Also, sports with a high risk for injuries can lead to secondary osteoarthrosis. Preventive exercises to strengthen the skeletal muscles seem to have a pivotal role. There are different therapeutic approaches to osteoarthrosis, which will be more important in the future. Exercise should be a core treatment for people with osteoarthritis, irrespective of age, comorbidity, pain severity, or disability. Exercise should include local muscle strengthening and general aerobic fitness.
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