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Updated: Jun 18, 2026

Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase
Published on: April 23, 2019
Odorant-linked ROS-GC subfamily membrane guanylate cyclase transduction system
Rameshwar K Sharma1, Teresa Duda
1Research Divisions of Biochemistry and Molecular Biology, The Unit of Regulatory and Molecular Biology, Salus University, Elkins Park, PA 19027, USA. rsharma@salus.edu
Abstract:
This review focuses on the principles of the Ca(2+)-modulated ROS-GC subfamily transduction system linked with the mammalian olfactory transduction field, its historical development, and the present day status on its constitution and operational mechanisms controlling the process of olfactory-transduction. Beginning parts of this article are freely borrowed from the earlier reviews of the authors (Sharma RK, Duda T, Venkataraman V, Koch KW, Curr Topics Biochem Res 6:111-144, 2004; Duda T, Venkataraman V, Sharma RK, Neuronal calcium sensor proteins, pp 91-113, Nova Science Publishers, Inc., 2007).
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