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Updated: Jun 18, 2026

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
Published on: March 26, 2019
Practical aspects of bedside cerebral hemodynamics monitoring in pediatric TBI
1Division of Neurosurgery, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa. Anthony.Figaji@uct.ac.za
Insights
Monitoring cerebral hemodynamics is crucial after traumatic brain injury (TBI) to prevent secondary injury. This review covers essential concepts and bedside monitoring techniques for cerebral blood flow and autoregulation.
Area of Science:
- Neuroscience
- Critical Care Medicine
- Medical Engineering
Background:
- Cerebral hemodynamic disturbances significantly impact secondary injury progression following traumatic brain injury (TBI).
- Neurocritical care interventions can adversely affect cerebral blood flow, often undetected by clinicians.
- Existing imaging techniques offer limited insight into the dynamic nature of cerebral hemodynamics.
Purpose of the Study:
- To review key pathophysiological concepts of cerebral hemodynamics after TBI.
- To discuss the principles, benefits, and limitations of current bedside monitoring techniques.
- To highlight the need for improved dynamic monitoring of cerebral blood flow.
Main Methods:
- Review of pathophysiological concepts related to TBI.
- Analysis of principles and applications of bedside monitoring techniques.
- Evaluation of transcranial Doppler, autoregulation monitoring, and local/regional cerebral blood flow measurement.
Main Results:
- Understanding cerebral hemodynamics is vital for managing TBI.
- Bedside monitoring offers potential for real-time assessment of cerebral blood flow.
- Current techniques have specific advantages and limitations that require careful consideration.
Conclusions:
- Effective management of TBI necessitates a thorough understanding of cerebral hemodynamics.
- Bedside monitoring techniques like transcranial Doppler and autoregulation assessment are essential tools.
- Further development and application of these techniques can improve patient outcomes in neurocritical care.
Introduction:
Disturbances in cerebral hemodynamics may have a profound influence on secondary injury after traumatic brain injury (TBI), and many therapies in the neurocritical care unit may adversely affect cerebral blood flow. However, the clinician is often unaware of this when it occurs because practical methods for monitoring cerebral hemodynamics by the bedside have been lacking. Current imaging studies only provide a snapshot of the brain at one point in time, giving limited information about a dynamic condition.
Discussion:
This review will focus on key pathophysiological concepts required to understand changes in cerebral hemodynamics after TBI and the principles, potential benefits, and limitations of currently available bedside monitoring techniques, including transcranial Doppler, autoregulation, and local/regional cerebral blood flow.

