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Published on: April 11, 2018
Giant retroperitoneal liposarcoma with mixed histological pattern: a rare presentation and literature review
Nikolaos S Salemis1, Evangelos Tsiambas, Andreas Karameris
12nd Department of Surgery, Army Veterans General Hospital, 10-12 Monis Petraki Str, 15121 Athens, Greece. nikos_salemis@hotmail.com
Background:
Retroperitoneal liposarcoma is a rare tumor that may grow to a considerable size before causing clinical symptoms. Mixed-type retroperitoneal liposarcoma is a very rare clinical entity.
Methods:
We herein describe a rare case of a 54-year-old female who was diagnosed with a giant retroperitoneal liposarcoma arising from the right perinephric space.
Results:
Radical nephrectomy and right salpingo-oophorectomy were necessary to achieve complete tumor excision. Histological examination revealed a mixed-type liposarcoma consisting of well-differentiated and pleomorphic elements and deep invasion into the renal parenchyma, which is quite infrequent. The patient was well and disease-free 12 months after surgery.
Conclusions:
Mixed-type retroperitoneal liposarcoma is a rare tumor. Aggressive surgical resection of the tumor together with adjacent structures, if necessary, is the mainstay of treatment.