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Related Concept Videos

Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
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Physical Methods for Controlling Microbial Growth: Radiation and Filtration

Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
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Methods for Controlling Microbial Growth

Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
Microbial Corrosion01:24

Microbial Corrosion

Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...
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Bioremediation is an environmentally sustainable process that employs living organisms—primarily microorganisms—to degrade or neutralize pollutants from contaminated environments. In oil spills and hydrocarbon pollution, bioremediation involves the use of hydrocarbon-degrading bacteria to transform toxic compounds into less harmful substances. This approach leverages natural microbial metabolic processes and is considered both cost-effective and ecologically favorable compared to physical or...
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Biofilm Removal Using Carbon Dioxide Aerosols without Nitrogen Purge
07:11

Biofilm Removal Using Carbon Dioxide Aerosols without Nitrogen Purge

Published on: November 6, 2016

Biofouling control using microparticles carrying a biocide.

C Ferreira1, R Rosmaninho, M Simoes

  • 1LEPAE, Departamento de Engenharia Quimica, Universidade do Porto, Rua Dr Roberto Frias, Porto, Portugal.

Biofouling
|November 26, 2009
PubMed
Summary
This summary is machine-generated.

This study developed microparticles to deliver antimicrobial agents, reducing their environmental impact. These drug-delivery systems effectively control microbial growth in planktonic and biofilm states.

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Evaluation of the Efficacy of Organic Peroxyacids for Eradicating Dairy Biofilms Using an Approach Combining Static and Dynamic Methods
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Published on: December 9, 2022

Area of Science:

  • Materials Science
  • Biotechnology
  • Environmental Science

Background:

  • Antimicrobial agents (AMB) have deleterious effects and overuse leads to environmental risks.
  • Drug-delivery systems offer a strategy to minimize AMB usage and enhance efficacy.
  • Microparticle-based delivery can control the release and activity of antimicrobial compounds.

Purpose of the Study:

  • To develop and assess microparticles for delivering quaternary ammonium compounds (QACs) as antimicrobial agents.
  • To evaluate the efficacy of these microparticles against Pseudomonas fluorescens in planktonic and biofilm states.
  • To investigate the stability and reusability of the antimicrobial-loaded microparticles.

Main Methods:

  • Microparticles were prepared using layer-by-layer (LBL) self-assembly on polystyrene cores.
  • The QAC benzyldimethyldodecyl ammonium chloride (BDMDAC) was loaded onto the microparticles.
  • CryoSEM and X-ray microanalysis were used for particle characterization; zeta potential measured surface charge.
  • Antimicrobial activity was tested against planktonic and biofilm P. fluorescens cells.

Main Results:

  • BDMDAC-coated microparticles demonstrated significant stability, with only 15% release over 18 months.
  • Effective minimum bactericidal concentrations were determined for BDMDAC-loaded particles against planktonic cells.
  • Exposure of P. fluorescens biofilms to the microparticles resulted in significant viability reduction (up to 87.2%).
  • Antimicrobial effects of microparticle-delivered BDMDAC were comparable to free BDMDAC.

Conclusions:

  • The developed microparticle system is a promising strategy for controlling microbial growth and biofouling.
  • This approach minimizes antimicrobial agent use, reducing environmental risks and public health concerns.
  • The layer-by-layer self-assembly technique offers a stable and potentially reusable method for antimicrobial drug delivery.