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Proteome-wide Quantification of Labeling Homogeneity at the Single Molecule Level
08:29

Proteome-wide Quantification of Labeling Homogeneity at the Single Molecule Level

Published on: April 19, 2019

A chemical labeling strategy for proteomics under nondenaturing conditions

Ghyslain Budin1, Martin Moune Dimala, Valérie Lamour

  • 1Laboratory of Functional Chemo-Systems UMR 7199, 74 Route du Rhin, Illkirch-Graffenstaden, France.

Chembiochem : a European Journal of Chemical Biology
|November 26, 2009
PubMed
Abstract

No abstract available in PubMed .

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...