Related Experiment Video
Updated: Jun 18, 2026
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Australasian Laparoscopic Colon Cancer Study shows that elderly patients may benefit from lower postoperative
R A Allardyce1, P F Bagshaw, C M Frampton
1Department of Surgery, University of Otago, Christchurch, New Zealand. randall.allardyce@otago.ac.nz
Background:
A retrospective analysis of age-related postoperative morbidity in the Australia and New Zealand prospective randomized controlled trial comparing laparoscopic and open resection for right- and left-sided colonic cancer is presented.
Methods:
A total of 592 eligible patients were entered and studied from 1998 to 2005.
Results:
Data from 294 patients who underwent laparoscopic and 298 who had open colonic resection were analysed; 266 patients were aged less than 70 years and 326 were 70 years or older (mean(s.d.) 70.3(11.0) years). Forty-three laparoscopic operations (14.6 per cent) were converted to an open procedure. Fewer complications were reported for intention-to-treat laparoscopic resections compared with open procedures (P = 0.002), owing primarily to a lower rate in patients aged 70 years or more (P = 0.002). Fewer patients in the laparoscopic group experienced any complication (P = 0.035), especially patients aged 70 years or above (P = 0.019).
Conclusion:
Treatment choices for colonic cancer depend principally upon disease-free survival; however, patients aged 70 years or over should have rigorous preoperative investigation to avoid conversion and should be considered for laparoscopic colonic resection.
Registration Number:
NCT00202111 (http://www.clinicaltrials.gov).
