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Updated: Jun 18, 2026

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

Does testosterone prevent early postoperative complications after gastrointestinal surgery?

Birendra Kumar Sah¹, Ming-Min Chen, Yi-Bing Peng

¹Department of General Surgery & Shanghai Institute of Digestive Surgery, Rui Jin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.

World Journal of Gastroenterology

|November 26, 2009

Summary

Low testosterone levels increase the risk of early postoperative complications in gastrointestinal surgery patients. This finding was observed in both sexes, highlighting testosterone as a potential predictor of adverse outcomes.

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Last Updated: Jun 18, 2026

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

Area of Science:

Reproductive endocrinology
Surgical oncology
Gastroenterology

Background:

Postoperative complications following gastrointestinal surgery are a significant concern.
The influence of sex hormones on surgical outcomes requires further elucidation.

Purpose of the Study:

To examine the association between sex hormones (estradiol, testosterone, progesterone) and early postoperative complications in patients undergoing gastrointestinal surgery.
To identify potential hormonal predictors of these complications.

Main Methods:

Analysis of peripheral venous blood samples from 65 patients undergoing gastric and colorectal surgery.
Measurement of estradiol, testosterone, and progesterone levels at various postoperative time points.
Correlation of hormone levels with the occurrence of postoperative complications.

Main Results:

Female patients exhibited a significantly higher rate of postoperative complications compared to male patients.
Lower testosterone levels were significantly associated with a higher incidence of postoperative complications (P < 0.05).
Testosterone levels, particularly at later postoperative stages, served as a predictor for increased complication rates.

Conclusions:

Low testosterone levels are linked to an increased susceptibility to postoperative complications in gastrointestinal surgery patients, irrespective of sex.
Further research is warranted to validate these findings and explore therapeutic implications.