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Updated: Jun 18, 2026
06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Thai venous stroke prognostic score: TV-SPSS
Niphon Poungvarin1, Naraporn Prayoonwiwat, Disya Ratanakorn
1Division of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. niphonp.thailand@gmail.com
Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|November 27, 2009
Summary
Researchers developed a new prognostic score for cerebral venous sinus thrombosis (CVST) in Thailand. This score helps predict poor outcomes in CVST patients, aiding clinical decision-making.
Area of Science:
- Neurology
- Vascular Neurology
- Clinical Epidemiology
Background:
- Cerebral venous sinus thrombosis (CVST) prognosis lacks study in Thailand.
- No simple prognostic score for CVST poor prognosis has been reported.
Purpose of the Study:
- To establish a simple and reliable prognostic score for CVST.
- To predict poor prognosis in Thai CVST patients.
Main Methods:
- Retrospective review of 194 CVST patient records from 1993-2005.
- Analysis of clinical features, risk factors, and outcomes (modified Rankin scale).
- Development of the Thai Venous Stroke Prognostic Score (TV-SPSS) using logistic regression.
Main Results:
- 26.3% of patients had a poor outcome (mRS 3-6); overall mortality was 8.4%.
- Four significant predictors identified: malignancy, low Glasgow Coma Scale (GCS), hemorrhagic infarction, and lateral sinus involvement.
- The Thai Venous Stroke Prognostic Score (TV-SPSS) was derived from these factors.
Conclusions:
- A pragmatic prognostic score for CVST outcome was developed with high sensitivity (93%) and low specificity (33%).
- Further validation in prospective populations is recommended.
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