Inherited thrombophilia in infertile women: implication in unexplained infertility
Luisa Casadei1, Francesco Puca, Laura Privitera
1Infertility Center, Department of Surgery, Tor Vergata University Hospital, Rome, Italy. Casadei@med.uniroma2.it
Abstract:
Many studies evaluating a possible relationship between inherited thrombophilia and the etiology of unexplained infertility have been performed recently. No significant difference in the prevalence of three genetic mutations associated with the increased risk of thrombophilia (Factor V Leiden G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677 T) was found in 100 infertile women with unexplained infertility when compared with 200 control fertile women without an infertility history.
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