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Published on: June 10, 2025
"Spider bite" lesions are usually diagnosed as skin and soft-tissue infections
1Department of Emergency Medicine, University of California, Irvine Medical Center, Orange, California 92868, USA.
Background:
Many people seek medical attention for skin lesions and other conditions they attribute to spider bites. Prior experience suggests that many of these lesions have alternate causes, especially infections with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA).
Objectives:
This study determined the percentage of emergency department (ED) patients reporting a "spider bite" who received a clinical diagnosis of spider bite by their physician vs. other etiologies, and if the diagnoses correlated with demographic risk factors for developing CA-MRSA infections.
Methods:
ED patients who reported that their condition was caused by a "spider bite" were prospectively enrolled in an anonymous, voluntary survey regarding details of their illness and demographic information. Discharge diagnoses were also collected and categorized as: spider bite, bite from other animal (including unknown arthropod), infection, or other diagnosis.
Results:
There were 182 patients enrolled over 23 months. Seven patients (3.8%) were diagnosed with actual spider bites, 9 patients (4.9%) with bites from other animals, 156 patients (85.7%) with infections, and 6 patients (3.3%) were given other diagnoses. Four patients were given concurrent diagnoses in two categories, and 8 (4.4%) did not have the diagnosis recorded on the data collection instrument. No statistically significant associations were found between the patients' diagnostic categories and the demographic risk factors for CA-MRSA assessed.
Conclusion:
ED patients reporting a "spider bite" were most frequently diagnosed with skin and soft-tissue infections. Clinically confirmed spider bites were rare, and were caused by black widow spiders when the species could be identified.
Insights
Most emergency department patients reporting spider bites are diagnosed with skin infections, not actual spider bites. True spider bites are rare, often caused by black widow spiders, and rarely linked to community-acquired methicillin-resistant Staphylococcus aureus risk factors.
Area of Science:
- Dermatology
- Emergency Medicine
- Infectious Diseases
Background:
- Many patients present to emergency departments with skin lesions attributed to spider bites.
- Previous observations suggest alternative causes, such as community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections, are more common.
Purpose of the Study:
- To determine the proportion of emergency department (ED) patients with "spider bite" complaints diagnosed as actual spider bites versus other conditions.
- To investigate correlations between diagnoses and demographic risk factors for CA-MRSA.
Main Methods:
- Prospective enrollment of ED patients reporting "spider bites" into an anonymous survey.
- Collection of patient-reported illness details, demographics, and discharge diagnoses.
- Categorization of diagnoses into spider bite, other animal bite, infection, or other.
Main Results:
- Out of 182 patients, only 3.8% were diagnosed with spider bites; 85.7% were diagnosed with infections.
- Bites from other animals accounted for 4.9%, and other diagnoses for 3.3%.
- No significant association was found between diagnostic categories and CA-MRSA risk factors.
Conclusions:
- Emergency department patients reporting spider bites are predominantly diagnosed with skin and soft-tissue infections.
- Confirmed spider bites are infrequent, with black widow spiders identified in confirmed cases.
- The study highlights the importance of accurate diagnosis for skin lesions presenting as "spider bites".
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