Related Experiment Video

Updated: Jun 18, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

Limiting activity at beta1-subunit-containing GABAA receptor subtypes reduces ataxia

Kelvin W Gee1, Minhtam B Tran, Derk J Hogenkamp

  • 1Department of Pharmacology, School of Medicine, University of California, Irvine, CA 92697, USA. kwgee@uci.edu

The Journal of Pharmacology and Experimental Therapeutics
|November 27, 2009
PubMed
Summary

New nonbenzodiazepine drugs targeting GABA(A) receptors show promise for anxiolytic effects. By selectively modulating specific receptor subunits, these compounds may reduce sedative side effects, offering a safer therapeutic approach.

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