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3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
Published on: May 19, 2015
Hemangiopericytoma in the lateral ventricle
Sakiko Suzuki1, Hiroshi Wanifuchi, Takashi Shimizu
1Department of Neurosurgery, Saiseikai Kurihashi Hospital. super.acuvy@gmail.com
Neurologia Medico-Chirurgica
|November 27, 2009
Summary
A rare intraventricular hemangiopericytoma (HPC) was surgically removed from a patient. The tumor did not recur after 4 years, suggesting radiation therapy may not be essential for low-risk HPC cases.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Background:
- Hemangiopericytoma (HPC) is a rare tumor that can occur in the brain's ventricles.
- Differentiating HPC from similar tumors like meningioma is crucial due to its aggressive nature.
Observation:
- A 31-year-old female presented with visual disturbances and headache, later diagnosed with a 5-cm right lateral ventricular mass.
- Ophthalmological examination revealed left hemianopsia and choked disc.
- Magnetic resonance imaging confirmed a homogeneously enhanced mass in the trigone of the right lateral ventricle.
Findings:
- The tumor was successfully and totally removed through a two-stage surgical procedure.
- Histological and immunochemical analyses confirmed the diagnosis of hemangiopericytoma (HPC).
- The patient experienced no recurrence or metastasis for 4 years post-surgery without adjuvant radiation therapy.
Implications:
- This case highlights the importance of accurate histological and immunochemical diagnosis for intraventricular HPC.
- Complete surgical resection may be sufficient for treating low-risk intraventricular HPC, potentially avoiding the need for radiation therapy.
- Further research is warranted to establish definitive treatment guidelines for intraventricular HPC based on tumor characteristics and MIB-1 staining index.
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