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Allergic Reactions

Allergic Reactions

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Allergic Reactions: Anaphylaxis

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

Allergic Drug Reactions

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Types of Toxins

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...

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Related Experiment Video

Updated: Jun 18, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Occupational allergy in strawberry greenhouse workers.

J A Patiwael¹, L G J Vullings, N W de Jong

¹Section of Allergology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands. j.patiwael@erasmusmc.nl

International Archives of Allergy and Immunology

|November 27, 2009

Summary

Occupational allergy to strawberry pollen affects greenhouse workers, causing work-related symptoms. This study confirms IgE-mediated sensitization to strawberry pollen in affected employees.

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Last Updated: Jun 18, 2026

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Area of Science:

Occupational Health
Allergology
Agricultural Science

Background:

Strawberry greenhouse workers face high exposure to potential allergens.
No prior occupational allergies were documented in this sector.
This study investigates work-related allergic symptoms and their underlying mechanisms.

Purpose of the Study:

To identify and characterize work-related allergic symptoms in strawberry greenhouse workers.
To demonstrate the role of immunoglobulin E (IgE)-mediated allergy in these symptoms.
To explore potential cross-reactivity with common pollen allergens.

Main Methods:

A survey of strawberry workers in the Netherlands identified symptomatic individuals.
Detailed investigation of three symptomatic workers included skin tests, serum-specific IgE, immunoblots, and nasal provocation tests.
Inhibition experiments were conducted to assess IgE cross-reactivity.

Main Results:

38.7% of surveyed workers reported work-related symptoms.
All three investigated workers showed sensitization to strawberry pollen via skin tests.
Immunological tests confirmed IgE binding to strawberry pollen in two workers, with partial cross-reactivity to birch/grass pollen in one.
Nasal provocation confirmed clinically relevant allergies in two subjects.

Conclusions:

A significant proportion of strawberry greenhouse employees experience work-related allergic symptoms.
Occupational allergy to strawberry pollen, mediated by IgE, is a likely cause of these symptoms.
Further research into allergen exposure and control measures is warranted.