Application of a new positioning device for isometric replacement in anterior cruciate ligament repair and reconstruction
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Updated: Oct 13, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
1Department of Surgery A, Heinrich-Heine-University Duesseldorf, F.R.G.
Abstract:
The functional effects of displacing the cruciate ligament attachments were studied in ten adult cadaver knees. On a systematic variation of the femoral and tibial attachment sites according to a three-dimensional raster scheme, a quantitative analysis of the absolute length and of motion-dependent changes in ligament isometry was performed. All insertion points deviating from the original anatomic landmarks did not accomplish biomechanical requirements. A femoral displacement had an increased effect on disturbing isometry compared to a tibial malposition. Although recommended by several authors, the "over-the-top" position gave the most unsatisfactory results with a maximum isometry failure of 10 mm. In cruciate ligament replacement a positioning guide with isometry testing capacity should be mandatory to ensure correct placement of bone tunnels. For this purpose a new positioning device which allows for isometry measurements before a bone channel is drilled is introduced and applied in an experimental setup.

