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Updated: Jun 18, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Adrenocortical carcinoma presenting with a peritoneal effusion
Leonidas D Arvanitis1, Lisa A Pitelka, Paolo Gattuso
1Department of Pathology, Rush University Medical Center, Chicago, IL 60611, USA. Leonidas_Arvanitis@rush.edu
Abstract:
In this report, we describe the fine-needle aspiration findings of a case of adrenocortical carcinoma (ACC) that spread to the peritoneal cavity in an 80-year-old female. Cytologically, the peritoneal fluid exhibited clusters and single, small uniform cells with round nuclei and a fine chromatin pattern, which in conjunction with the immunohistochemical stains was diagnostic of ACC. Although ACC is the most common malignant neoplasm of the adrenal gland, its metastatic spread to the peritoneal cavity is exceptionally unusual.
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