Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Timing and Consequences on Behavior01:08

Timing and Consequences on Behavior

In operant conditioning, the timing of reinforcement is crucial. For animals like rats and cats, immediate reinforcement (within a few seconds) is much more effective than delayed reinforcement. For example, a food reward for a rat needs to follow within 30 seconds of pressing a bar to be effective. 
Humans, however, can respond to delayed reinforcers. We often make decisions between immediate small rewards and delayed larger rewards. This ability to delay gratification is a significant factor...
Mixing Time01:19

Mixing Time

The concept of mixing time is significant in producing a uniform concrete mix with the required strength. The mixing period starts once all components are in the mixer. Initially, the mixer is charged with 10% of the water, followed by the consistent addition of solids and then 80% of the water. The remaining water is added later, within the first quarter of the mixing period. The minimum mixing time varies according to the mixer's capacity; for example, mixers with up to 1 cubic yard capacity...
Framing Effects03:26

Framing Effects

Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in different ways based on the...
Generation Time01:22

Generation Time

Bacterial generation time, the period required for a bacterial population to double during its exponential growth phase, serves as a critical measure of microbial growth dynamics under optimal conditions. This parameter varies significantly across bacterial species and can be influenced by factors such as temperature, pH, and the availability of nutrients. For example, Escherichia coli can achieve a generation time of approximately 20 minutes, while Mycobacterium tuberculosis exhibits a much...
Chronopharmacokinetics: Time-Dependent Pharmacokinetics01:20

Chronopharmacokinetics: Time-Dependent Pharmacokinetics

Chronopharmacokinetics studies the temporal change in drug absorption and elimination. These changes can be cyclical or non-cyclical. Cyclical changes occur over a regular interval, while non-cyclical changes occur over a longer, irregular period.
Time-dependent pharmacokinetics refers to non-cyclical changes in drug rate processes over a period of time. It can lead to nonlinear pharmacokinetics, where the relationship between drug concentration and time is not proportional. Non-cyclical...
Noncompartmental Analysis: Statistical Moment Theory00:56

Noncompartmental Analysis: Statistical Moment Theory

Noncompartmental analyses leverage statistical moment theory to examine time-related changes in macroscopic events, encapsulating the collective outcomes stemming from the constituent elements in play. Statistical moment theory is a mathematical approach used to describe the time course of drug concentration in the body without assuming a specific compartmental model. SMT provides insights into drug absorption, distribution, metabolism, and elimination by treating drug concentration versus time...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Knowledge preservation in the era of big science and AI: strategies for sustainable scientific research.

Nature communications·2026
Same author

Constitutively active RAS prolongs Cdc42 signalling, while MAPK signalling is attenuated during fission yeast mating.

PLoS genetics·2026
Same author

Expression Dynamics and Genetic Compensation of Cell Cycle Paralogues in <i>Saccharomyces cerevisiae</i>.

Cells·2025
Same author

Plant cold acclimation and its impact on sensitivity of carbohydrate metabolism.

NPJ systems biology and applications·2025
Same author

Enhancement of essential cofactors for <i>in vivo</i> biocatalysis.

Faraday discussions·2024
Same author

Data integration strategies for whole-cell modeling.

FEMS yeast research·2024
Same journal

Overlapping gut microbiome signatures in aging and disease are characterized by enrichment of medication-associated oral microbes in the gut.

FEBS letters·2026
Same journal

Csk binding to integrin β3 is regulated by tyrosine and threonine phosphorylation of β3.

FEBS letters·2026
Same journal

Mixed-class J-domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly.

FEBS letters·2026
Same journal

Design and analysis strategies for robust microbiome ageing research.

FEBS letters·2026
Same journal

Reconstructing enzyme evolution by protein engineering.

FEBS letters·2026
Same journal

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates.

FEBS letters·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
16:23

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Published on: February 26, 2014

Timing matters.

Edda Klipp1

  • 1Theoretical Biophysics, Humboldt-Universität Berlin, Berlin, Germany. edda.klipp@rz.hu-berlin.de

FEBS Letters
|November 28, 2009
PubMed
Summary
This summary is machine-generated.

Systems biology examines cellular dynamics over time. This review highlights characteristic times and time hierarchies, emphasizing the crucial role of timing in yeast and microorganism research for better experimental and theoretical insights.

More Related Videos

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes
09:27

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Published on: January 19, 2024

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks
09:04

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks

Published on: March 16, 2015

Related Experiment Videos

Last Updated: Jun 18, 2026

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
16:23

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Published on: February 26, 2014

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes
09:27

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Published on: January 19, 2024

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks
09:04

Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks

Published on: March 16, 2015

Area of Science:

  • Cellular and Molecular Biology
  • Systems Biology
  • Biophysics

Background:

  • Cells are fundamental units of life, existing within spatial and temporal contexts.
  • Systems biology aims to elucidate cellular composition, organization, and dynamic behaviors.
  • Understanding cellular dynamics requires analyzing temporal properties.

Purpose of the Study:

  • To review measures for dynamic properties in cellular systems.
  • To discuss the significance of characteristic times, time hierarchy, and time-dependent responses.
  • To underscore the importance of temporal considerations in experimental and theoretical systems biology.

Main Methods:

  • Literature review of dynamic properties in systems biology.
  • Analysis of characteristic times and time hierarchies.
  • Case studies from yeast and micro-organism systems biology.

Main Results:

  • Identification and review of key measures for cellular dynamic properties.
  • Demonstration of the importance of time hierarchy in biological systems.
  • Examples illustrating time-dependent cellular responses.

Conclusions:

  • Temporal dynamics are critical for a comprehensive understanding of cellular function.
  • Integrating timing into experimental design and theoretical models enhances biological insights.
  • The principles discussed are broadly applicable to yeast and micro-organism systems biology.