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Updated: Jun 18, 2026

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
Published on: June 15, 2017
Signaling by neuronal tyrosine kinase receptors: relevance for development and regeneration
Barbara Hausott1, Isil Kurnaz, Srecko Gajovic
1Division of Neuroanatomy, Medical University Innsbruck, Muellerstrasse 59, Innsbruck, Austria.
Abstract:
Receptor tyrosine kinase activation by binding of neurotrophic factors determines neuronal morphology and identity, migration of neurons to appropriate destinations, and integration into functional neural circuits as well as synapse formation with appropriate targets at the right time and at the right place. This review summarizes the most important aspects of intraneuronal signaling mechanisms and induced gene expression changes that underlie morphological and neurochemical consequences of receptor tyrosine kinase activation in central and peripheral neurons.
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