Related Experiment Video
Updated: Aug 11, 2026

A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation
Published on: April 27, 2019
Patient evaluation for cardiac transplantation
1Henry Ford Heart and Vascular Institute, Henry Ford Hospital, Detroit, MI 48202.
Insights
Careful screening of heart transplant candidates is crucial for improving survival and quality of life in end-stage heart failure patients. A multidisciplinary approach ensures optimal use of scarce donor organs and successful long-term outcomes.
Area of Science:
- Cardiology
- Transplantation Medicine
- Health Services Research
Background:
- End-stage heart failure necessitates advanced treatment options like cardiac transplantation.
- Donor organ scarcity, high costs, and significant patient/family burden highlight the need for careful selection.
- Successful transplantation requires ruling out conditions that could compromise the procedure or immunosuppression.
Purpose of the Study:
- To emphasize the critical importance of comprehensive pre-transplant candidate screening.
- To outline the essential criteria for evaluating potential heart transplant recipients.
- To advocate for a multidisciplinary team approach in candidate selection.
Main Methods:
- Evaluation of symptomatic, functional, hemodynamic, and psychosocial eligibility.
- Exclusion of coexisting hemodynamic or comorbid conditions.
- Multidisciplinary team assessment involving patients and families.
Main Results:
- Comprehensive screening identifies suitable candidates for cardiac transplantation.
- Thorough evaluation minimizes risks associated with transplantation and immunosuppression.
- Optimizes the utilization of limited donor organs.
Conclusions:
- Rigorous and comprehensive screening is paramount for successful cardiac transplantation.
- A multidisciplinary approach ensures optimal patient selection and resource allocation.
- Careful candidate evaluation maximizes the benefits of heart transplantation for improved survival and quality of life.
Abstract:
The aim for cardiac transplantation is to improve the quality of life and the survival in patients with end-stage heart failure. Given the scarcity of donor organ availability, the expense of the transplantation process and follow-up care, as well as the tremendous emotional burden the process places on a patient and his/her family, it is essential to carefully screen potential candidates for their symptomatic, functional, hemodynamic, and psychosocial eligibility, and to rule out coexisting hemodynamic or comorbid conditions that would jeopardize successful transplantation and immunosuppression. Comprehensive screening of potential transplant candidates, which is best accomplished by a multidisciplinary team approach working closely with patients and their families, is essential to insure that maximum benefit is derived from this scarce and valuable resource.
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Cardiomyopathy V: Interprofessional Care
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure
Kidney Transplant III: Nursing Management

