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Related Concept Videos

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
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Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
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Common Respiratory Disorders

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Related Experiment Video

Updated: Jun 18, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

Common cold decreases lung function in infants with recurrent wheezing.

J Mallol1, V Aguirre, G Wandalsen

  • 1Department of Paediatric Respiratory Medicine, Hospital CRS El Pino, University of Santiago de Chile (USACH), Santiago, Chile. jmallol@vtr.ne

Allergologia Et Immunopathologia
|December 1, 2009
PubMed
Summary

Common acute viral respiratory infections (colds) significantly reduce lung function in infants with recurrent wheezing (RW). This effect is more pronounced in expiratory flows, highlighting the impact of colds on infant respiratory health.

Related Experiment Videos

Last Updated: Jun 18, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

Area of Science:

  • Pediatric pulmonology
  • Respiratory medicine
  • Infant health

Background:

  • Recurrent wheezing (RW) in infants is frequently exacerbated by common acute viral respiratory infections (colds).
  • Quantitative data on the impact of colds on lung function in infants with RW is lacking.
  • Understanding this impact is crucial for managing infant respiratory conditions.

Purpose of the Study:

  • To quantitatively assess the effect of common colds on forced expiratory lung function parameters in infants with recurrent wheezing.
  • To determine the extent of lung function impairment during common colds in this population.

Main Methods:

  • Spirometric lung function was assessed in 28 infants with RW during both cold episodes and asymptomatic periods.
  • Measurements included forced expiratory parameters from raised lung volume.
  • Study design involved random assessment to compare lung function under different conditions.

Main Results:

  • Common colds led to a significant decrease in all measured forced expiratory parameters.
  • Flow rates (FEF(50%), FEF(75%), FEF(25-75%)) showed the most marked reduction, becoming abnormal in most infants.
  • Factors like family asthma history and environmental tobacco exposure did not correlate with the degree of lung function decrease during colds, although maternal smoking during pregnancy was linked to lower asymptomatic expiratory flows.

Conclusions:

  • Common colds significantly impair lung function in infants with recurrent wheezing.
  • The reduction in expiratory flows indicates substantial airway obstruction during common colds.
  • Further research may explore long-term implications and specific management strategies for these infants.