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Related Experiment Video

Updated: Jun 18, 2026

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
08:22

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Published on: July 21, 2013

[Reversible cerebral vasoconstriction syndrome].

Anne Ducros1

  • 1Centre d'urgences céphalées, Pôle neurosensoriel tête et cou, APHP, Hôpital Lariboisière, F-75010 Paris, France. anne.ducros@lrb.aphp.fr

Presse Medicale (Paris, France : 1983)
|December 1, 2009
PubMed
Summary

Reversible cerebral vasoconstriction syndrome (RCVS) is common and often missed. It involves temporary brain artery spasms, frequently triggered by substances or postpartum, causing thunderclap headaches and potential complications.

Area of Science:

  • Neurology
  • Vascular Neurology
  • Neuroimaging

Context:

  • Reversible cerebral vasoconstriction syndrome (RCVS) is increasingly recognized as a significant cause of neurological emergencies.
  • It is characterized by transient, reversible cerebral artery vasoconstriction and dilation.
  • RCVS often presents with thunderclap headaches and can be triggered by vasoactive substances or occur postpartum.

Purpose:

  • To summarize the epidemiology, clinical presentation, diagnostic challenges, and management of RCVS.
  • To highlight the characteristic radiological findings and the importance of follow-up imaging.
  • To discuss potential complications and treatment strategies for RCVS.

Summary:

  • RCVS affects individuals around age 42, with a slight female predominance.

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  • The syndrome typically manifests as recurrent thunderclap headaches, with complications like hemorrhage and ischemic events occurring within weeks.
  • Diagnosis relies on "string and beads" angiography, though initial imaging may be normal, requiring repeat studies; nimodipine is a common but not always effective treatment.
  • Impact:

    • Improved understanding of RCVS incidence and underdiagnosis.
    • Enhanced diagnostic criteria and imaging protocols for RCVS.
    • Informed clinical practice regarding triggers, complications, and treatment of RCVS.