Related Experiment Video
Updated: Jun 18, 2026

Anesthesia and Intubation of Preadolescent Mouse Pups for Cardiothoracic Surgery
Published on: June 2, 2022
Anesthetic management of a patient with cleidocranial dysplasia undergoing various obstetric procedures
A Ioscovich1, D Barth, A Samueloff
1Department of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center, Hebrew University, Jerusalem, Israel. aioscovich@gmail.com
Insights
Cleidocranial dysplasia (CCD) presents unique anesthetic challenges due to anatomical abnormalities. This case report details managing anesthesia for a patient with CCD across multiple obstetric and gynecologic procedures.
Area of Science:
- Anesthesiology
- Medical Genetics
Background:
- Cleidocranial dysplasia (CCD) is a rare autosomal dominant disorder.
- Patients exhibit craniofacial, dental, and skeletal abnormalities.
- These anomalies can lead to significant perioperative complications.
Observation:
- The study focuses on the anesthetic management of a young woman with CCD.
- The patient underwent multiple procedures: four cesarean sections, one vaginal delivery, and a dilatation and curettage.
- Various anesthetic techniques were employed during these interventions.
Findings:
- Anesthetic management for patients with CCD is complex.
- Difficult airway and challenges with regional anesthesia are common concerns.
- Successful management requires careful consideration of the patient's specific anatomical features.
Implications:
- This case highlights the importance of tailored anesthetic strategies for CCD patients.
- It underscores the need for vigilance regarding potential airway and neuraxial complications.
- Improved understanding can enhance patient safety during surgical and obstetric procedures.
Abstract:
Patients with cleidocranial dysplasia, a rare autosomal dominant genetic syndrome, possess abnormal anatomical features of the head, mouth, neck and spinal column. These features may result in perioperative problems such as difficult airway and complicated regional anesthesia. We report the anesthetic management of a young woman with cleidocranial dysplasia undergoing four caesarean sections, one vaginal delivery and a dilatation and curettage, employing different modes of anesthesia. Anesthetic management in this disorder presents challenges for both general and neuraxial anesthesia.
Related Concept Videos
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Parenteral Anesthetics: Overview
Stages of General Anesthesia
Skeletal Muscle Relaxants: Therapeutic Uses
Inhalational Anesthetics: Overview
