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Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report
Fengzhi Feng1, Yang Xiang, Yang Cao
1Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, and Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China.
Background:
Spinal canal metastasis secondary to gestational trophoblastic neoplasia (GTN) is a rare condition.
Case:
A 21-year-old female presented with symptoms of cauda equina compression by an extradural metastasis from GTN. The patient received multiagent chemotherapy combined with intrathecal methotrexate administration. Her neurologic symptoms improved remarkably after the cessation of chemotherapy. During the 21-month follow-up period, she was asymptomatic and has shown overall improvement in well-being.
Conclusion:
Spinal canal metastasis of GTN is a possibility that must be considered in young women with a history of hydatidiform mole who have neurologic symptoms or signs, which were improved completely by chemotherapy alone in this case.
