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Updated: Jun 18, 2026

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
Published on: September 29, 2011
[Aging and cancerogenesis--atavistic processes inherited from modular ancestors: hypothesis]
Abstract:
The regulatory physiological system of a unitary organism, i.e. the organism reproducing only by sexual way, includes along with others the three following mechanisms guaranteeing reliability of the life interruption: 1) senescence; 2) cancer; 3) disintegration in the organism under influence of the factors which action exceeds adaptive abilities of the organism. The three mechanisms are inherited from modular, i.e. reproduced not only by sexual but by asexual way, ancestors, in which organisms the destructive processes were reversible. The conversion of the mechanisms of reversible disintegration into mechanisms of irreversible disintegration is the consequence of progressive evolution.
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