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BioMEMS and Cellular Biology: Perspectives and Applications
Published on: October 1, 2007
What is life? Bio-physical perspectives
1N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, 4 ul. Kosygina, Moscow 117977, Russia. academy@endeav.org
Advances in Gerontology = Uspekhi Gerontologii
|December 2, 2009
Summary
Life emerges from atomic systems with energy inflow, characterized by dynamic reactivity. This perspective defines living objects using thermodynamics and mathematical state functions, applicable from molecules to humans.
Area of Science:
- Thermodynamics
- Biophysics
- Chemical Physics
Background:
- Life originates and evolves within gravitationally bound atomic systems under specific energy inflow conditions.
- Living objects exhibit structural dynamic reactivity to energy, encompassing structures from molecules to humans.
- These systems are thermodynamic quasi-closed supramolecular entities within larger natural open systems, evolving near equilibrium.
Purpose of the Study:
- To define life as a consequence of universal laws, particularly thermodynamics.
- To propose a framework of hierarchical thermodynamics and a principle of substance stability.
- To provide a definition of life based on exact sciences, avoiding non-physical models.
Main Methods:
- Quantification of living systems using mathematical "state functions" (temperature, pressure, composition).
- Application of thermodynamic principles to understand the emergence and evolution of life.
- Analysis of life from a geocentric perspective, focusing on universal laws.
Main Results:
- Life is presented as a natural consequence of universal laws, specifically thermodynamics.
- Hierarchical thermodynamics and the principle of substance stability offer a new perspective on living systems.
- Living structures form at the nanolevel due to environmental variations driving diversity.
Conclusions:
- Life can be defined as a bio-chemical-physical phenomenon grounded in exact sciences.
- This thermodynamic perspective offers a physically sound model for understanding life.
- The study reframes life not as unique but as an emergent property of universal physical laws.
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