[Interrelations of cancer of hormone dependent tissues and other non-infectious diseases: aging aspect]

The group of main noncommunicable diseases (NCDs) includes cardio- and cerebrovascular pathology, cancer, chronic nonspecific respiratory states, diabetes mellitus, osteoporosis, unipolar depression, obesity, etc. Tumors of hormone dependent tissues compose about 35-45% of the whole cancer morbidity. The attempts to understand place of these tumors among other NCDs and analyze their interrelationships with regard to age and aging represent a vital task of contemporary oncoendocrinology. On the ground of accumulated data one can conclude that although principal NCDs are diagnosed mainly in the course of second half of human life, the maturing of their hormonal and metabolic bases is extended in time, rather often starts several decades before clinical appearance and demonstrates diverse character of the associations with different constituents of this group of diseases. As a result it may give rise for the absence of parallelism in age-specific incidence of several main NCDs, especially at concluding stages of ontogenesis.