[Functional results of partial nephrectomy for kidney tumors]

Area of Science:

• Nephrology
• Surgical Oncology
• Radiology

Background:

• Organ-sparing surgery is a key approach for kidney neoplasms.
• Assessing functional outcomes post-surgery is crucial for patient prognosis.
• Radioisotopic methods and serum creatinine levels are used to evaluate kidney function.

Purpose of the Study:

• To analyze the functional results of organ-sparing kidney operations.
• To investigate the correlation between warm ischemia time and kidney function.
• To identify prognostic factors for kidney function after surgery.

Main Methods:

• Radioisotopic methods were employed to assess kidney function.
• Serum creatinine levels were monitored in 31 patients.
• Functional outcomes were analyzed in relation to surgical parameters.

Main Results:

• Functional outcomes of organ-sparing operations are directly dependent on warm renal ischemia duration.
• Warm ischemia exceeding 15 minutes can cause ultrastructural nephron damage.
• A decrease in filtration level by 20-30% was observed with prolonged ischemia.
• Sudden changes in serum creatinine post-operation indicate long-term kidney function prognosis.

Conclusions:

• The duration of warm renal ischemia is a critical factor in the success of organ-sparing kidney operations.
• Local hypothermia is recommended when renal blood flow is interrupted for over 10-15 minutes to preserve kidney function.
• Monitoring serum creatinine levels provides valuable insights into long-term kidney function post-surgery.