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Genetic variation of 15 autosomal STR loci in a Somali population
Andreas O Tillmar1, Gerd Bäckström, Kerstin Montelius
1National Board of Forensic Medicine, Department of Forensic Genetics and Forensic Toxicology, Artillerigatan 12, SE-58758 Linköping, Sweden. andreas.tillmar@rmv.se
Abstract:
Allele frequencies for 15 autosomal STR loci included in the AmpFlSTR Identifiler kit (CSF1PO, D13S317, D16S539, D18S51, D19S433, D21S11, D2S1338, D3S1358, D5S818, D7S820, D8S1179, FGA, TH01, TPOX, VWA) were obtained from the analysis of 404 individuals with Somali origin. The overall match probability for the 15 studied loci was 1 in 1.18 x 10(17) and the combined power of exclusion was 0.999997676. Deviation from Hardy-Weinberg equilibrium was observed for locus D2S1338 after correction for multiple testing. When comparing allele frequencies with five other African populations (Karamoja (Uganda), Mozambique, Tanzania and two other Somali population sample sets), only the Somali populations did not show significant differences for any of the tested loci.
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