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Orocaecal transit time in Duchenne muscular dystrophy
S H Korman1, B Bar-Oz, E Granot
1Department of Paediatrics, Hadassah University, Jerusalem.
Archives of Disease in Childhood
|January 1, 1991
Summary
Gastrointestinal motility is often affected in Duchenne muscular dystrophy. This study found no significant differences in small intestinal transit time between patients with muscular dystrophy and healthy individuals.
Area of Science:
- Gastroenterology
- Neuromuscular Disorders
Background:
- Smooth muscle degeneration is a potential complication in Duchenne muscular dystrophy.
- Previous reports suggest gastric hypomotility in Duchenne muscular dystrophy patients.
Purpose of the Study:
- To investigate small intestinal motility in patients with Duchenne muscular dystrophy.
- To compare orocaecal transit time in muscular dystrophy patients and healthy controls.
Main Methods:
- Fasting orocaecal transit time was measured.
- Participants included patients with advanced Duchenne muscular dystrophy, other muscular dystrophies, and healthy controls.
Main Results:
- No significant differences in fasting orocaecal transit time were observed between the groups.
- The study found no evidence of impaired small intestinal motility in Duchenne muscular dystrophy patients.
Conclusions:
- Small intestinal motility appears to be preserved in advanced Duchenne muscular dystrophy.
- Findings contrast with previous reports of gastric hypomotility, suggesting a more complex picture of gastrointestinal involvement.