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Anal fissures associated with targeted therapies in ovarian cancer

Jennifer Squires1

  • 1Medical Oncology Branch of the National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. squiresj@mail.nih.gov

Clinical Journal of Oncology Nursing
|December 2, 2009
PubMed

Insights

Targeted therapies improve ovarian cancer outcomes but can cause anal fissures, disrupting treatment. Advanced practice nurses play a vital role in managing these fissures to maintain patient quality of life during ovarian cancer therapy.

Area of Science:

  • Gynecologic Oncology
  • Gastroenterology Nursing

Background:

  • Ovarian cancer is a significant cause of cancer mortality in women.
  • Targeted therapies offer improved outcomes for ovarian cancer patients.
  • Anal fissures are a common and disruptive side effect of these advanced treatments.

Observation:

  • Anal fissures can negatively impact treatment adherence and patient quality of life.
  • The management of anal fissures requires specialized nursing knowledge and skills.
  • Early diagnosis and intervention are key to mitigating the effects of anal fissures.

Findings:

  • Advanced practice nurses are essential in the diagnosis and management of anal fissures in ovarian cancer patients.
  • Effective fissure management by nurses helps maintain treatment continuity.
  • Nursing interventions improve the quality of life for patients undergoing targeted cancer therapy.

Implications:

  • Integrating specialized anal fissure management into ovarian cancer care pathways is crucial.
  • Nurses' role in managing treatment side effects enhances overall patient care and outcomes.
  • Further research into optimizing nursing protocols for treatment-related toxicities is warranted.

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