Related Experiment Video
Updated: Jun 18, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
Published on: May 12, 2023
Cost of vaccine administration among pediatric practices
Judith E Glazner1, Brenda Beaty, Stephen Berman
1Department of Health Systems, Management, and Policy, Colorado School of Public Health, Aurora, Colorado, USA.
Insights
The variable costs for administering childhood immunizations to providers averaged $11.51 per injection. Some health plans reimburse practices less than the actual cost of vaccine administration.
Area of Science:
- Pediatric healthcare economics
- Public health policy
- Immunization program management
Background:
- Understanding the financial sustainability of immunization services is crucial for maintaining high vaccination rates.
- Pediatric practices face financial challenges in delivering essential childhood immunizations.
- Accurate cost data is needed to inform reimbursement policies.
Purpose of the Study:
- To document and analyze the variable costs incurred by healthcare providers for delivering childhood immunizations.
- To compare these costs with existing reimbursement rates from various health plans.
Main Methods:
- Variable costs, including staff time, supplies, and waste disposal, were documented in ten private pediatric practices.
- Payment data from health plans was collected and analyzed for 37 different agreements.
- A simulation model was used to adjust for the small sample size.
Main Results:
- The average variable cost per immunization injection (excluding vaccine cost) was $11.51.
- Non-routine activities, such as inventory, record provision, and parent inquiries, contributed significantly to costs.
- Over one-third of payment agreements provided reimbursement below the combined variable costs for administering two vaccines.
Conclusions:
- Variable costs associated with vaccine administration can exceed reimbursement from certain insurers and health plans.
- This discrepancy poses a financial challenge for pediatric practices providing immunization services.
- Reimbursement policies may need adjustment to ensure the financial viability of childhood immunization programs.
Objective:
The goal was to describe variable costs to providers of delivering childhood immunizations.
Methods:
We documented variable costs (costs that vary with the amount of services rendered), including time spent by pediatric staff members and physicians on immunization-related activities, as well as supply costs and medical waste disposal costs. Ten private pediatric practices in the Denver, Colorado, metropolitan area participated in the study. Among the 7 practices that provided us with payment data, 8 health plans were mentioned by > or = 2 practices. There were 37 different agreements between the health plans and practices for vaccine administration payments.
Results:
The total documented variable cost per injection (excluding vaccine cost) averaged $11.51, calculated from the following categories: nursing time, $1.71; billing services, $2.67; nonroutine services, $1.64; registry use, $0.96; physician time, $4.05; supplies, $0.36; medical waste disposal, $0.12. Nonroutine activities primarily included performing vaccine inventory and ordering, providing vaccination records to requesters, and answering parent telephone questions about vaccinations. With the use of a simulation model to compensate for the small number of participating practices, the calculated total variable cost per injection was $11.83. When 2 vaccines were administered, we compared the sum of the 2 payments with the sum of the 2 variable costs ($23.02). More than one third of the payment agreements (13 of 37 agreements) paid the practices less than the combined variable costs for 2 immunizations.
Conclusion:
This study shows that the variable costs of vaccine administration exceeded reimbursement from some insurers and health plans.
Related Concept Videos
Vaccinations
Vaccine Production
Drug Dosing: Infants and Children
Dosage Interval and Administration Route: Determination Methods
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices
Pharmacokinetics in Pediatric Patients: Drug Distribution

