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Updated: Jun 18, 2026

09:46
Fabrication and Characterization of High-Q Silicon Nitride Membrane Resonators
Published on: August 8, 2025
Versatile ultrathin nanoporous silicon nitride membranes
Ivan Vlassiouk1, Pavel Y Apel, Sergey N Dmitriev
1Department of Physics and Astronomy, University of California, Irvine, CA 92697, USA. vlassiouk@gmail.com
Summary
Researchers developed silicon nitride membranes with precisely controlled nanopore shapes and sizes for advanced biosensing and separations. These novel membranes offer tunable porosity and enhanced molecular discrimination capabilities.
Area of Science:
- Materials Science
- Nanotechnology
- Biophysics
Background:
- Nanopore membranes are crucial for biosensing and separation, mimicking biological functions.
- Pore density, shape, and surface chemistry dictate membrane performance.
Purpose of the Study:
- To engineer silicon nitride (SiN) membranes with fully controllable nanopore characteristics.
- To demonstrate the separation capabilities of these engineered membranes for biomolecules.
Main Methods:
- Utilized the track-etching technique to create ultrathin freestanding SiN membranes.
- Fabricated membranes with tunable porosity (1 to billions of pores/cm²) and conical/double-conical nanopores.
- Chemically modified pore walls to tune separation properties.
Main Results:
- Achieved precise control over membrane porosity, pore geometry, and surface chemistry.
- Demonstrated effective separation of dye and protein molecules based on charge and size via electrostatic interactions.
- Conical/double-conical pores exhibited higher fluxes and shorter effective lengths compared to cylindrical pores.
Conclusions:
- Developed versatile SiN nanopore membranes with tunable properties for advanced separation and biosensing.
- Conical pore geometry offers significant advantages for high-flux separations and single biomolecule detection, including DNA analysis.

