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Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

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Related Experiment Video

Updated: Jun 18, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

SPECT in acute pulmonary embolism.

Paul D Stein1, Leonard M Freeman, H Dirk Sostman

  • 1Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan 48341-5023, USA. steinp@trinity-health.org

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|December 2, 2009
PubMed
Summary
This summary is machine-generated.

Single-photon emission computed tomography (SPECT) demonstrates high accuracy for diagnosing acute pulmonary embolism, often outperforming planar ventilation-perfusion (V/Q) imaging. SPECT offers a sensitive and specific alternative for evaluating this critical condition.

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Point-of-Care Lung Ultrasound in Adults: Image Acquisition
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A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

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Published on: September 6, 2024

Point-of-Care Lung Ultrasound in Adults: Image Acquisition
09:17

Point-of-Care Lung Ultrasound in Adults: Image Acquisition

Published on: March 3, 2023

Area of Science:

  • Radiology
  • Nuclear Medicine
  • Cardiopulmonary Imaging

Background:

  • Acute pulmonary embolism (PE) diagnosis relies on imaging.
  • Ventilation-perfusion (V/Q) imaging is a common diagnostic tool.
  • Limited data exist on SPECT's accuracy for PE using objective references.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of SPECT for acute pulmonary embolism.
  • To compare SPECT performance against planar V/Q imaging.

Main Methods:

  • Systematic review of investigations evaluating SPECT in acute PE.
  • Analysis of studies using objective reference standards for PE diagnosis.
  • Comparison of sensitivity and specificity of SPECT versus planar V/Q imaging.

Main Results:

  • SPECT sensitivity was generally ≥90% across studies.
  • SPECT specificity was also generally ≥90%.
  • SPECT sensitivity was higher than planar V/Q in 4 out of 5 investigations.

Conclusions:

  • SPECT demonstrates high sensitivity and specificity for acute pulmonary embolism.
  • SPECT appears more advantageous than planar V/Q imaging for PE diagnosis.
  • Further standardization of SPECT methods may enhance its utility.