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Updated: Jun 18, 2026

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System

Published on: October 22, 2020

Secondhand smoke exposure and depressive symptoms.

Frank C Bandiera¹, Kristopher L Arheart, Alberto J Caban-Martinez

¹Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

Psychosomatic Medicine

|December 2, 2009

Summary

This summary is machine-generated.

Secondhand smoke (SHS) exposure is linked to increased depressive symptoms in adults who have never smoked. This study highlights the need for further investigation into the mechanisms behind this association.

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A New Method for Inducing a Depression-Like Behavior in Rats

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Published on: February 22, 2018

Area of Science:

Environmental Health
Public Health
Psychiatry

Background:

Tobacco smoking is strongly linked to depression.
The impact of secondhand smoke (SHS) exposure on mental health, specifically depression, remains under-evaluated.

Purpose of the Study:

To investigate the association between SHS exposure and depressive symptoms.
To determine if SHS exposure affects individuals who have never smoked.

Main Methods:

Utilized data from the 2005-2006 National Health and Nutrition Examination Survey (NHANES).
Measured SHS exposure using serum cotinine levels in U.S. adults (aged >=20).
Assessed depressive symptoms via the Patient Health Questionnaire and analyzed data using zero-inflated Poisson regression.

Main Results:

Serum cotinine-confirmed SHS exposure showed a positive association with depressive symptoms in never-smokers.
This association persisted after adjusting for demographic, lifestyle, and medical factors.
No significant variation in the association was observed by gender, and no link was found in former smokers.

Conclusions:

SHS exposure is positively associated with depressive symptoms among never-smokers.
Further research is warranted to elucidate the underlying biological and psychological mechanisms connecting SHS exposure and depression.