Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Accuracy of common drug screen tests.

J G Schwartz1, P R Zollars, A O Okorodudu

  • 1Department of Pathology, University of Texas Health Science Center, San Antonio 78284-7750.

The American Journal of Emergency Medicine
|March 1, 1991
PubMed
Summary

Drug testing assays show high efficiency for cocaine detection. For marijuana, latex agglutination inhibition assays offer a cost-effective screening option, though other methods provide higher accuracy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Particles internalization, oxidative stress, apoptosis and pro-inflammatory cytokines in alveolar macrophages exposed to cement dust.

Environmental toxicology and pharmacology·2014
Same author

The potential benefits and adverse effects of phytic Acid supplement in streptozotocin-induced diabetic rats.

Advances in pharmacological sciences·2014
Same author

Lead, mercury, cadmium, chromium, nickel, copper, zinc, calcium, iron, manganese and chromium (VI) levels in Nigeria and United States of America cement dust.

Chemosphere·2012
Same author

Lupus Vulgaris.

British medical journal·2010
Same author

Tuberculosis and the N.H.S. Act.

British medical journal·2010
Same author

Adenosine deaminase activity in subjects with normal pregnancy, pregnancy induced hypertension and pre-eclampsia.

West African journal of medicine·2010

Area of Science:

  • Clinical Chemistry
  • Toxicology
  • Forensic Science

Background:

  • Urine drug testing is crucial in emergency settings for identifying substance abuse.
  • Accurate and rapid detection methods are essential for patient management and public health.

Purpose of the Study:

  • To compare the efficiency of a new latex agglutination inhibition assay (Abuscreen OnTrak) against established methods for detecting cocaine and marijuana in urine specimens.
  • To evaluate the performance of various drug abuse assays, including mass spectrometry, enzyme immunoassays, and fluorescence polarization immunoassay.

Main Methods:

  • Analysis of 40 urine specimens positive for cocaine and/or marijuana.
  • Comparison of Abuscreen OnTrak with mass spectrometry (reference standard), Syva ETS, Syva EMIT-st, and Abbott TDx.

Related Experiment Videos

  • Standardized cutoff concentrations: 100 µg/L for marijuana, 300 µg/L for cocaine and metabolites.

    • Main Results:

    • All tested methods demonstrated 95% efficiency in detecting cocaine and its metabolites.
    • Marijuana detection efficiency varied from 70% (Abuscreen OnTrak) to 90% (Syva ETS).
    • Mass spectrometry served as the reference standard for substance identification.

    Conclusions:

    • Commercially available drug abuse screening assays offer rapid and accurate results.
    • While all methods are effective for cocaine detection, variations exist in marijuana detection efficiency.
    • Cost-effective and user-friendly assays are available for routine drug screening in clinical and forensic settings.