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Central nervous system blastomycosis in a dog.

M Casey Gaunt¹, Susan M Taylor, Moira E Kerr

¹Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4. casey.gaunt@usask.ca

The Canadian Veterinary Journal = La Revue Veterinaire Canadienne

|December 2, 2009

Summary

A golden retriever experienced progressive neurological issues, diagnosed as blastomycosis affecting the brainstem. This fungal infection required confirmation through cytology and urine antigen testing, ultimately verified post-mortem.

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Area of Science:

Veterinary Neurology
Mycology
Infectious Diseases

Background:

Blastomycosis is a fungal infection caused by *Blastomyces dermatitidis*.
Neurologic involvement in systemic blastomycosis can occur but is less common.
Canine blastomycosis diagnosis often relies on clinical signs, cytology, and antigen testing.

Observation:

An adult golden retriever presented with progressive neurologic dysfunction, localized to the brainstem.
Clinical signs included ataxia, circling, and altered mentation.
Physical examination revealed proprioceptive deficits and cranial nerve abnormalities.

Findings:

Fine-needle aspiration cytology of a lymph node was consistent with blastomycosis.
A positive blastomycosis urine antigen test supported disseminated infection.
Necropsy confirmed systemic blastomycosis with significant brainstem lesions.

Implications:

This case highlights the importance of considering blastomycosis in dogs with neurologic signs, even without typical respiratory or cutaneous lesions.
Diagnostic methods like urine antigen testing are crucial for early detection of systemic fungal infections.
Understanding the varied presentations of blastomycosis is vital for effective veterinary treatment and management.