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Gender differences among korean patients with coronary spasm.
Ju Hwan Lee1, Hyunsang Lee, Myung Hwan Bae
1Department of Internal Medicine, CHA University, CHA Gumi Medical Center, Gumi, Korea.
Korean Circulation Journal
|December 2, 2009
Summary
Korean male patients with coronary spasm were more likely to smoke and consume alcohol than females. Female patients were younger, highlighting significant gender differences in coronary spasm characteristics.
Area of Science:
- Cardiology
- Internal Medicine
- Vascular Biology
Background:
- Coronary spasm, a condition affecting the heart's arteries, has not been well-defined regarding gender differences in Korean populations.
- Understanding these differences is crucial for accurate diagnosis and tailored treatment strategies.
Purpose of the Study:
- To investigate and define the specific gender differences observed in Korean patients diagnosed with coronary spasm.
- To analyze clinical characteristics associated with coronary spasm in relation to patient gender.
Main Methods:
- A retrospective analysis was conducted on 104 patients diagnosed with coronary spasm at Kyungpook National University Hospital from 2001 to 2008.
- Coronary vasospasm was provoked using intracoronary ergonovine maleate in cases with suspected spasm and no significant coronary stenosis.
Main Results:
- Female patients with coronary spasm were significantly younger (52+/-7 years) compared to male patients (57+/-10 years).
- Female patients exhibited lower rates of smoking (19% vs. 65%) and alcohol consumption (43% vs. 89%) compared to males.
- Triglyceride levels were the only other clinical characteristic that showed a significant difference between genders.
Conclusions:
- The study identified distinct gender-based characteristics in Korean patients with coronary spasm, with males being more prevalent smokers and alcohol consumers.
- Female patients were younger and had lower rates of smoking and alcohol consumption, suggesting potential gender-specific pathogenetic factors.
- Further research is warranted to elucidate the role of gender in the development and progression of coronary spasm.
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