Related Experiment Video
Updated: Jun 18, 2026

02:21
Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
Published on: March 15, 2024
Pyoderma gangranosum of the penis
Tae Heung Kim1, Seung Young Oh, Soon Chul Myung
1Department of Urology, College of Medicine, Chung-Ang University, Seoul, Korea.
Journal of Korean Medical Science
|December 2, 2009
Summary
Pyoderma gangrenosum can affect the penis and urethra, requiring medical and surgical treatment. This case highlights successful reconstructive surgery for penile pyoderma gangrenosum.
Area of Science:
- Urology
- Dermatology
- Surgical Reconstruction
Background:
- Pyoderma gangrenosum (PG) is a rare, ulcerative neutrophilic dermatosis.
- Penile involvement of PG is exceptionally uncommon, posing diagnostic and therapeutic challenges.
Observation:
- A patient presented with penile pyoderma gangrenosum extending into the distal urethra.
- The ulcerative process led to significant tissue destruction requiring complex management.
Findings:
- Systemic treatment with prednisolone and thalidomide was initiated.
- Successful reconstructive surgery was performed using a scrotal island flap for penile reconstruction.
Implications:
- This case expands the understanding of pyoderma gangrenosum presentation and management.
- Highlights the potential for surgical intervention in severe penile PG cases.
Related Concept Videos
Penis
The penis serves a dual role in sexual reproduction and urination. It consists of three main regions: the glans penis, the body, and the root, each with distinct functions and unique anatomical features.
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Cirrhosis I: Introduction
Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Peripheral Artery Disease I: Introduction
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...