Related Experiment Video
Updated: Jun 18, 2026

Knee Arthrocentesis in Adults
Published on: February 25, 2022
Adverse events from diagnostic and therapeutic joint injections: a literature review
Cynthia Peterson1, Juerg Hodler
1Radiology, Orthopaedic University Hospital of Balgrist, Forchstrasse 340, 8008, Zürich, Switzerland. cynthia.peterson@balgrist.ch
Abstract:
This review article classifies the various adverse reactions arising from intra-articular injections by severity, diagnostic category, and whether they are due to corticosteroid, local anesthetic or viscosupplementation injections. Life-threatening and serious adverse events from intra-articular injections are rare and range from local complications to systemic afflictions. Measures to reduce the likelihood of an adverse event occurring are outlined and patients with significant features in their clinical histories, predisposing them to adverse events, are highlighted.