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Updated: Jun 18, 2026

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)
Published on: April 7, 2021
Acute respiratory distress syndrome: rapid and significant response to volume-controlled inverse ratio ventilation--a
Nahid Aghdaii1, Seyede Zahra Faritous, Forouzan Yazdanian
1Depart. of Anesthesiology, Shahid Rajaii Cardiovascular Medical Center, Iran University of Medical Sciences, Tehran, lran. aghdaii@yahoo.com
Abstract:
Pulmonary complications following cardiopulmonary bypass (CPB) are relatively common, with up to 12% of patients experiencing acute lung injury (ALI). The treatment for ALI or acute respiratory distress syndrome (ARDS) is primarily supportive with specific modes of mechanical ventilation. We report a 46-year-old man withARDS after cardiac surgery whose arterial oxygenation was surprisingly improved 1 hour after using volume-controlled inverse ratio ventilation (VC-IRV).
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