Related Experiment Video

Updated: Jun 18, 2026

Implantation of hiPSC-derived Cardiac-muscle Patches after Myocardial Injury in a Guinea Pig Model
07:03

Implantation of hiPSC-derived Cardiac-muscle Patches after Myocardial Injury in a Guinea Pig Model

Published on: March 18, 2019

[Myocarditis exacerbation in a child undergoing inguinal herniopasty after viral infection]

Dusica Simić, Irina Milojević, Ivana Budić

    Srpski Arhiv Za Celokupno Lekarstvo
    |December 3, 2009
    PubMed

    Insights

    A child developed heart failure after general anesthesia due to undiagnosed rubella-induced myocarditis. Prompt treatment improved his condition, highlighting the need for viral infection screening before pediatric surgery.

    Area of Science:

    • Pediatric Cardiology
    • Infectious Diseases
    • Anesthesiology

    Background:

    • General anesthesia and surgery can suppress the immune system, posing risks for children with recent infections.
    • The incidence of childhood myocarditis remains largely unknown.

    Observation:

    • A 7-year-old boy experienced sudden heart failure during anesthesia for inguinal hernia repair.
    • Clinical signs included hypotension, pulmonary edema, decreased oxygen saturation, and cardiac arrhythmias.
    • Echocardiography revealed diminished left ventricular contractility, with elevated troponin I and CK-MB levels indicating myocardial injury.

    Findings:

    • The patient's symptoms were attributed to rubella-induced myocarditis, confirmed by elevated IgM titers to rubella.
    • Hemodynamic stability was achieved with dopamine and furosemide.
    • Treatment with intravenous immunoglobulin, corticosteroids, and heart failure management led to recovery, with ejection fraction reaching 68%.

    Implications:

    • This case underscores the importance of considering viral infections, such as rubella, in pediatric patients presenting with cardiac complications post-anesthesia.
    • It highlights the need for updated protocols for elective surgery in children with recent viral infections.
    • Early diagnosis and management of myocarditis are crucial for favorable outcomes in pediatric patients.
    Abstract

    More Related Videos

    Gene Transfer for Ischemic Heart Failure in a Preclinical Model07:35

    Gene Transfer for Ischemic Heart Failure in a Preclinical Model

    Published on: May 15, 2011

    Related Concept Videos

    Myocarditis III: Medical Management01:14

    Myocarditis III: Medical Management

    Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
    Myocarditis I: Introduction01:21

    Myocarditis I: Introduction

    Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
    Myocarditis IV: Nursing Management01:22

    Myocarditis IV: Nursing Management

    Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
    Myocarditis II: Clinical Features and Diagnostic Tests01:27

    Myocarditis II: Clinical Features and Diagnostic Tests

    Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
    Endocarditis III: Medical Management01:18

    Endocarditis III: Medical Management

    Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
    Pericarditis III: Medical Management01:17

    Pericarditis III: Medical Management

    The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...