Related Experiment Video
Updated: Jun 18, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[News in childhood asthma therapy]
Insights
This review highlights recent advances in paediatric asthma therapy, emphasizing phenotype-based treatment. Early diagnosis and cautious use of inhaled corticosteroids in infants are crucial for effective asthma management.
Area of Science:
- Paediatric Pulmonology
- Asthmology
Context:
- Intensified research in paediatric pulmonology and asthmology.
- Growing interest in epidemiology, genetics, and virology for predicting childhood asthma.
- Numerous studies on early wheezing, risk factors, and the natural course of childhood asthma.
Purpose:
- To review recently published articles on phenotype-based asthma therapy.
- To enhance the understanding of asthma and asthma-like syndromes in children.
- To provide insights into current expert recommendations for paediatric asthma management.
Summary:
- Phenotype-based approaches are advancing paediatric asthma therapy.
- Early diagnosis and prompt, accurate treatment are paramount.
- Inhaled corticosteroids are not routinely recommended for very young infants without a clear positive effect.
- Long-term use of inhaled corticosteroids requires careful scrutiny.
Impact:
- Facilitates a better understanding of paediatric asthma and related syndromes.
- Informs clinical practice regarding early diagnosis and treatment strategies.
- Guides the judicious use of inhaled corticosteroids in paediatric populations.
- Promotes evidence-based therapeutic decisions for childhood asthma.
Abstract:
Research in the field of paediatric pulmonology, especially asthmology, has been intensified for the last couple of years. A large number of studies describe early wheezing episodes, risk factors, natural course of early childhood asthma. Besides this, literature shows a growing interest in epidemiology, genetics and virusology as predictive factors for development and clinical course of childhood asthma. In this paper, the authors are providing a review of recently published articles on asthma therapy based on phenotypes in terms of better understanding of asthma and asthma-like syndromes. Paediatric respiratory experts worldwide are equally positive in the following statements: real diagnosis leads to real therapy as soon as possible; inhaled corticosteroids are not recommended in very young infants especially if a positive effect is missing; long-term therapy with inhaled corticosteroids has to be scrutinized.
Related Concept Videos
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-I: Introduction
Asthma-IV: Nursing Management
First, in...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Asthma I: Introduction
