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Updated: Jun 18, 2026

Injection of Porcine Adipose Tissue-Derived Stroma Cells via Waterjet Technology
Published on: November 23, 2021
Cellular therapy for treatment of stress urinary incontinence
Klaudia Stangel-Wójcikiewicz1, Stec Małgorzata, Dmitriy Nikolavsky
1Departament of Gynecology and Oncology, Collegium Medicum Jagiellonian University of Kraków, Poland.
Abstract:
A critical mechanism to maintain urinary continence in women and men is the striated muscle sphincter (rhabdosphincter) that forms a ring around the mid urethra. Cellular therapy and the use of stem cells transplanted into the site of the rhabdosphincter in a setting of stress urinary incontinence may augment sphincter regeneration. Implanted cells may also release trophic factors promoting muscle and nerve integration into this muscle. We hereby review the use of cellular therapy for SUI and our experience with the development of muscle-derived stem cells.
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